What happens if a tumor ruptures

Extensive-stage small cell lung cancer was subsequently diagnosed. Four days following hospital admittance, oliguria was detected along with increasing serum levels of creatinine, potassium, phosphorous, and uric acid. The diagnosis of TLS was based on the characteristic electrolyte abnormalities.

Show More. Login Register. Enjoying our content? Results: Of the patients who underwent surgical resection of their tumors, 53 patients experienced a tumor rupture. Median follow-up period was 68 months. The authors conducted a retrospective observational study including 15, women with stage IA-IC1 epithelial ovarian cancer who underwent surgery between and in Japan.

The cohort included women with clear cell histology, as well as with endometrioid, with mucinous, and with serous histology. A total of women had capsule rupture during surgery. Women with clear cell ovarian cancer were most likely to have capsule rupture during surgery, at This was followed by endometrioid Tumor rupture appeared associated with shorter OS among patients treated with or without imatinib after surgery for gastrointestinal stromal tumors, or GIST, according to results of a post-hoc observational study published in JAMA Surgery.

However, researchers found no association between microscopic margin status without tumor rupture and shorter survival. On the contrary, tumor rupture is confirmed to be associated with a much worse outcome for GIST located at any site, regardless of adjuvant therapy use. Researchers lacked a clear understanding of the association between quality of surgery and OS among patients with localized GIST.

For this reason, Gronchi and colleagues pooled data from a randomized, open-label, phase 3 study including patients median age, 59 years; range, ; Researchers stratified randomization according to cancer center, risk category, tumor site and quality of surgery, defined as macroscopic complete resection with negative margins R0 vs.

Researchers included tumor rupture in the R1 category and in separate analysis. They assessed risk for death with and without imatinib according to margins status.